Journal of Biochemical Sciences

Thermodynamics and Bioenergetics

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Cellular thermodynamics explores the energy transformations within living systems, applying the principles of thermodynamics to biochemical processes. It delves into concepts like Gibbs free energy, enthalpy, and entropy to understand cellular work and reactions. Maintaining an energy balance is critical for cellular functions, and this discipline elucidates how organisms utilize and exchange energy to sustain life processes. Cellular thermodynamics provides a foundational framework for comprehending the energetics of biological systems, influencing fields such as biochemistry and metabolic research. Bioenergetics is concerned with the energy conservation and conversion processes in a living cell, particularly in the inner membrane of the mitochondrion.